I have a rather interesting history with
phentermine.
I decided to give it a try about four years ago after twenty years of fighting my weight, reaching my peak at 220 lbs. (I'm a 42 y.o. female, btw, 5'4".) I went to my doctor and asked for a script for phentermine or anything that would help, and he told me that "all [i] need to do" is exercise more and go on a low-carb, high-protein
diet...right, like I hadn't tried that over and over again without success. So, I did what any reasonable person who gets annoyed with thin doctors who think that willpower conquers all would do, and found a site online where I could order it.
Starting with
30mgs a day, I found that not only did I have energy that I hadn't felt since I weighed 130 lbs (not speedy, just normal), but I'd lost 30 pounds in three months. After that the tolerance kicked in and I upped my next order to the
37.5 dose. Didn't notice much difference there. I stopped losing weight but continued to feel energetic...but at least I didn't gain any weight back. A few months later life changed drastically for me and losing weight and buying meds definitely became a low priority.
Fast forward to October of 2004. Still hadn't gained back the thirty pounds that I'd originally lost with phentermine, but I'd meanwhile dieted on and off with some marginal success. Still, my cravings and lack of energy had entirely stalled my efforts in losing the sixty or so pounds that I truly wanted to lose. So...I figured I'd give phentermine a shot again. I had some concerns that my tolerance would still be a roadblock, but I hoped that since some years had passed since last using it that my tolerance would go back to what it was when I first started taking it.
I had success again with 30mgs. In fact, I had to remind myself to eat at least 1000 calories a day, and since I really had no desire to eat (or crave, or binge, or graze) it was very easy to eat foods that were actually nutritious that ordinarily I'd have snubbed because they were good for me. That was pretty cool, I gotta admit. Unfortunately, tolerance kicked in quickly this time, and while I did lose weight successfully, I had to double my dose every morning. I'm no medical expert, but I'm sure this can't be wonderful for one's cardiovascular system. But you know what? After being obese for so long -- while also remembering what it felt like to be a "normal" sized person way-back-when -- I didn't worry too much about my heart.
What *did* worry me were some side effects that I'd never experienced previously. I was used to the constant thirst, the only side effect I'd ever noticed in the past and actually I had no problem with this since it forced me to increase my
water intake, and that's never a bad thing, right? But the worst thing was that I found my jaw clenching and tightening to the point where I'd be in true pain by the end of the day. Granted, I've had TMJ surgery three times due to a softball accident back in my college days but normally I don't experience any problem with pain from that. This time, however, the clenching and spasms were almost intolerable. Plus, my tolerance was sky-high and the drug was basically useless by this point.
So, for about two months I gave up on phentermine, figuring that I'd run the course with it and it would no longer work in my body. Then one day I started thinking about it (ever notice how when you're totally bored out of your skull at work, you tend to think of things that just kinda pop in your mind, and then run with it?) The first time, years ago, that I'd ordered phentermine, I'd gone with the blue/white capsules (can't think of the company that makes them offhand) and had success. When I tried again last fall, I ordered the 30mg YELLOW capsules because they were cheaper. And I believe I mean that in every sense of the word. They simply sucked. I don't know if I required twice the (self-prescribed) dosage because of previous tolerance issues, or if because these were inferior meds, but I do suspect that the jaw clenching was due to this brand.
My next refill, I went back to the 30mg BLUE capsules and hey! No tolerance issues in the beginning, and absolutely NO muscle spasms. My energy level was up, and my appetite was down, and I was losing an average of ten to fifteen pounds a month. Unfortunately, after three months the tolerance thing kicked in again and so did my appetite. I realized that I'd probably run my course with phentermine for the time being, and it was time to either stop diet meds or try something different.
I'm about 25 lbs away from my target weight right now and I hate to lose the momentum that I've had for the last seven months or so, so I have switched to Didrex, 50mgs t.i.d. Frankly, as far as physical effects go I have noticed no difference from those I first had when originally trying phentermine (the BLUE ones, a few years back.) This, in my opinion, is a good thing, because it worked. The only drawbacks I see are 1) I have to remember to take it three times a day instead of just once in the morning, and 2) Didrex is a heck of a lot more expensive than phentermine. My hope is that I'll reach my goal with Didrex, and perhaps at that point I can start back with the phentermine, even with the tolerance issues, as a means of maintaining the weight I desire, because I realize that the anorectic effect is pretty much gone now. But if it'll help me maintain by curbing the urge to graze and binge and still keep up my energy level, I'm willing to continue to shell out the bucks for a maintenance dose of phentermine.
Of course, I'm not doctor, and I'm sure many would be appalled by my method of self-medicating. But hey, this is my story, for what it's worth.